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14 Nov 2019
  • Victorian Comprehensive Cancer Centre

Co-opting our knowledge of brain development towards developmental reprogramming of brainstem gliomas

We invite you to hear from special international guest and expert in neuro-oncology, Dr David Eisenstat from the University of Alberta, Canada.

Dr Eisenstat’s seminar will cover:

  • Review central nervous system development with a focus on interneuron versus oligodendrocyte cell fate decisions and migration
  • Overview of the distal-less (DLX) family of homeobox transcription factors and their gene networks responsible for CNS development
  • Apply these concepts towards translation to the paediatric high-grade gliomas, especially diffuse intrinsic pontine glioma (DIPG)

Image Eisenstat small

Dr David D. Eisenstat, MD, MA, FRCPC

Dr David Eisenstat is Professor and Chair of the Department of Oncology at the University of Alberta. He holds cross-appointments in the Departments of Medical Genetics and Paediatrics. David was the Division Director, Paediatric Immunology, Haematology/Oncology, Palliative Care and Environmental Health (iHOPE Division) from 2011-2017, has held the Muriel and Ada Hole Kids with Cancer Society Chair in Paediatric Oncology since 2011 and was formerly the Co-Director of the Cancer Research Institute of Northern Alberta (CRINA) from 2014-2017.

His laboratory is interested in the interface between cell fate, cancer and development.  

Dr Eisenstat obtained his MD from the University of Toronto in 1985. He completed his paediatrics residency at the Hospital for Sick Children (HSC) in 1990.  After a Clinical Fellowship in Paediatric Haematology-Oncology at HSC, David joined the Laboratory of Molecular Neuro-Oncology in the Brain Tumour Research Centre at the University of California, San Francisco (UCSF).  In 1993, funded by the Medical Research Council of Canada, David worked with Dr. John Rubenstein in the Laboratory of Developmental Neurobiology and was awarded a master’s degree in Neuroscience from UCSF in 1997. In 1998, David was a Clinical Fellow in Paediatric and Adult Neuro-Oncology at the University of Texas M.D. Anderson Cancer Centre, Houston Texas. 

Dr Eisenstat began his first faculty appointment at the University of Manitoba, Winnipeg, Canada, in 1999.  He was Director of the Advanced Degrees in Medicine at the University of Manitoba from 2007-2011 overseeing the MD/PhD and B.Sc. (Medicine) programs, and Senior Investigator in the Manitoba Institute of Cell Biology as well as Director of Neuro-Oncology (adult and paediatric) for Cancer Care Manitoba, from 1999 to 2011. He established the Canadian National Medical Student Research Symposium in 2009; this event continues to be held in Winnipeg on an annual basis.

Dr Eisenstat is especially proud to have been awarded the Aubie Angel Young Investigator Award in Clinical Research in 2004, the Health Sciences Graduate Students Association Distinction in Mentorship Award in 2006, both from the University of Manitoba, and the Paediatric Chairs of Canada Paediatric Academic Leadership – Clinical Educator Award in 2010.

Date: 14 November, 2019

Time: 12.00pm - 1.00pm

Venue: VCCC Lecture Theatre C

Can't be there in person. Register for webinar

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